Immunosuppressive therapy in liver transplantation: contribution to nursing

Authors

  • Raphael Colares de Sá Hospital Universitário Walter Cantídio - Universidade Federal do Ceará
  • Camilo Reuber de Sousa Soares Universidade Federal do Ceará

DOI:

https://doi.org/10.13037/ras.vol14n50.3992

Keywords:

liver transplantation, immunosuppressive agents, nursing

Abstract

Introduction: All patients undergoing liver transplantation require lifelong treatment with immunosuppressive agents in order to avoid graft rejection. Objective: This study aims to characterize the immunosuppressive therapy used in liver transplantation and propose nursing interventions to manage this therapeutic group. Method: This is a documental, bibliographical and descriptive research conducted from clinical protocols of liver transplantation from the transplant centers of Ceará, Brazil. From the protocols, the immunosuppressive agents used in liver transplantation were identified and then characterized about its clinical and pharmacological characteristics from the specialized and current literature in the field of medicine and pharmacology. It then proceeded with the discussion about the proper management of this therapy by the nursing team from the evidences of Micromedex and UpToDate bases. Results: Immunosuppressive agents have specific characteristics related to their indications, mechanisms of action, adverse effects and drug interactions, in which knowing and understanding these characteristics are fundamental to the management of the therapy aiming to an adequate graft function. In this scenario, the nursing team has responsibility not only in the administration of immunosuppressive agents, but also in monitoring the results, preventing complications and promoting health education for patients and families. Conclusions: The management of immunosuppressive agents requires nursing professionals scientifically grounded about the characteristics and related care in order to ensure a safe and effective therapy, as in to support the patient with relevant guidelines, thus ensuring their empowerment in the process of self-care.

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Author Biographies

Raphael Colares de Sá, Hospital Universitário Walter Cantídio - Universidade Federal do Ceará

Enfermeiro. Especialista em Transplante de Órgãos e Tecidos pelo programa de Residência Multiprofissional do Hospital Universitário Walter Cantídio/UFC.

Camilo Reuber de Sousa Soares, Universidade Federal do Ceará

Enfermeiro. Especialista em Terapia Intensiva. Mestre em fisiologia pela Universidade Estadual do Ceará.

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Published

2016-11-23

Issue

Vol. 14 No. 50 (2016)

Section

ARTIGOS DE REVISÃO

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