The influence of risk factors for cardiovascular diseases on cardiac autonomic modulation

Authors

  • Pedro Henrique Rodrigues Universidade Estadual Paulista
  • Mariana Borges de Oliveira Universidade Estadual Paulista
  • Leonardo Cazelato Universidade Estadual Paulista
  • Eduardo Federighi Baisi Chagas Universidade Estadual Paulista
  • Robison José Quitério Universidade Estadual Paulista

DOI:

https://doi.org/10.13037/ras.vol14n49.3712

Keywords:

autonomic nervous system, risk factors, cardiovascular diseases

Abstract

Introduction: Autonomic nervous system changes is an independent risk factor for cardiocirculatory events, which can be studied by analysis of heart rate variability (HRV). Objective: To investigate the influence of risk factors for cardiovascular disease and medications on cardiac autonomic modulation. Methods: A sample of 23 adults with at least one cardiovascular risk factor, aged 50 and 70 years. Case histories and anthropometric evaluations were conducted. In the sitting condition of rest, heart rate (HR) and RR intervals were analyzed in the time domain (HR and RMSSD), frequency (LF, HF and LF/HF), and the Poincaré plot (SD1, SD2 and SD1/SD2 ). Results: There was a correlation between the presence of a sedentary lifestyle and changes in normal levels of LF (nu) and LF/HF (R = 0.479 and R = 0.439), as well the number of risk factors and the FC (R = 0.512). Testing the influence of medications using on changes in HR and HRV was found correlation of the Angiotensin II converting enzyme inhibitors with LF (nu) and LF/HF (R = -0.505 and R = -0.550). Conclusion: A sedentary lifestyle is associated with hyperactivation of the sympathetic modulation, and a greater number of risk factors for cardiovascular disease is associated with elevated resting HR, characterizing increased stress on the cardiovascular system. But the Angiotensin II converting enzyme inhibitors is related to reductions in sympathetic modulation and sympathetic-vagal balance, which is a favorable indicator for morbidity’s control.

 

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References

Pereira JC, Barreto SM, Passos VMA. Perfil de risco cardiovascular e autoavaliação da saúde no Brasil: estudo de base populacional. Rev Panam Salud Publica. 2009;25(6):491-8.

Sociedade Brasileira de Cardiologia/Sociedade Brasileira de Hipertensão/Sociedade Brasileira de Nefrologia. VI Diretrizes Brasileiras de Hipertensão. Arq Bras Cardiol. 2010;95(1 Supl 1):1-51.

Kimura T, Matsumoto T, Akiyoshi M, Owa Y, Miyasaka N, Aso T, et al. Body fat and blood lipids in postmenopausal women are related to reting autonomic nervous system activity. Eur J Appl Physiol. 2006;97(5):542-7.

Vanderlei LCM, Pastre CM, Hoshi RA, Carvalho TD, Godoy MF. Noções básicas de variabilidade da frequência cardíaca e sua aplicabilidade clínica. Rev Bras Cir Cardiovasc. [Internet]. 2009[citado em 2015 out. 12];24(2):205-217. Disponível em: http://dx.doi.org/10.1590/S0102-76382009000200018

Chagas EFB, Bonfim MR, Brondino NCM, Monteiro HL. Exercício físico e fatores de risco cardiovasculares em mulheres obesas na pós-menopausa. Rev Bras Med Esporte. 2015;21(1):65-9.

Sociedade Brasileira de Cardiologia. I Diretriz Brasileira de Diagnóstico e Tratamento da Síndrome Metabólica. Arq Bras Cardiol. 2005;84 Supl I.

Benedetti TRB, Mazo GZ, Barros MVG. Aplicação do Questionário Internacional de Atividade Física para avaliação do nível de atividades físicas de mulheres idosas: validade concorrente e reprodutibilidade teste-reteste. Rev Bras Ci e Mov. 2004;12(1):25-34.

Colpani V, Spritzer PM, Lodi NP, Dorigo GG, Miranda IAS, Hahn LB, et al. Atividade física de mulheres no climatério: comparação entre auto-relato e pedômetro. Rev Saúde Pública. 2014;48(2):258-65.

World Health Organization. Obesity: preventing and managing the global epidemic. Report of a World Health Organization Consultation. Geneva: World Health Organization; 2000. WHO Obesity Technical Report Series, n. 284.

Gamelin FX, Berthoin S, Bosquet L. Validity of Polar S810 Heart Rate Monitor to Measure R-R Intervlas at Rest. Med Sci Sports Exerc. 2006;38(5):887-93.

Task Force of The European Society of Cardiology of the North American Society of Pacing Electrophysiology. Heart Rate Variability Standards of Measurement, Physiological Interpretation, and Clinical Use. Circulation. 1996;93(5):1043-65.

Yang XS, Beck GJ, Wilkoff BL. Redefining Normal Sinus Heart Rate. J Am Coll Cardiol. 1995;25(2 Suppl 1):193.

Brennan M, Palaniswami M, Kamen P. Do existing measures of Poincare plot geometry reflect nonlinear features of heart rate variability. IEEE Trans Biomed Eng. 2001;48(11):1342-7.

Dawson B, Trapp RG. Bioestatística básica e clínica. 3. ed. Rio de Janeiro: McGraw-Hill; 2001.

Bard JM, Charles MA, Juhan-vague I, Vague P, Andre P, Safar M, et al. Accumulation of triglyceride-rich lipoprotein insubjects with abdominal obesity: the biguanides and the prevention of the risk of obesity (BIGPRO) 1 study. Arterioscler Thromb Vasc Biol. 2001;21:407-14.

Gomes F, Telo DF, Souza HP, Nicolau JC, Halpern A, Serrano Jr CV. Obesidade e doença arterial coronariana: papel da inflamação vascular. Arq Bras Cardiol. [Internet]. 2010[citado em: 2015 out. 12];94(2):273-9. Disponível em: http://www.arquivosonline.com.br/pesquisartigos/PDFS/2010/9402/9402021.PDF

Santos D, Sichieri R. Índice de massa corporal e indicadores antropométricos de adiposidade em idosos. Rev Saúde Pública [Internet]. 2005[citado em: 2015 out. 12];39(2):163-8. Disponível em: http://www.scielo.br/pdf/rsp/v39n2/24037.pdf

Paschoal MA, Fontana CC. Método do limiar de variabilidade da frequência cardíaca aplicado em pré-adolescentes obesos e não obesos. Arq Bras Cardiol. 2011;96(6):450-6

Ferreira CCC, Peixoto MRG, Barbosa MA, Silveira EA. Prevalência de fatores de risco cardiovascular em idosos usuários do sistema único de saúde de Goiânia. Arq Bras Cardiol. 2010;95(5):621-8

Petersen LC, Chinazzo H, Saldanha C, Basso M, Garcia P, Bartholomay E, et al. Fatores de risco cardiovasculares e comorbidades em ambulatórios de cardiologia da região metropolitana de Porto Alegre, RS. Rev AMRIGS. 2011;55(3):217-23.

Thayer JF, Yamamoto SS, Brosschot JOSF. The relationship of autonomic imbalance, heart rate variability and cardiovascular disease risk factors. Int J Cardiol Heart Vasc. 2010:141(2):122-31.

Singh JP, Larson MG, O’donnell CJ, Wilson PF, Tsuji H, Lloyd-Jones DM, et al. Association of hyperglycemia with reduced heart rate variability (The Framingham Heart Study). Am J Cardiol. 2000;86(3):309-12.

Christensen JH, Toft E, Christensen MS, Schmidt EB. Heart rate variability and plasma lipids in men with and without ischaemic heart disease. Atherosclerosis. 1999;145:181-6.

Ferreira RA, Barreto SM, Giatti L. Hipertensão arterial referida e utilização de medicamentos de uso contínuo no Brasil: um estudo de base populacional. Cad Saúde Pública. 2014;30(4):815-26.

Motter FR, Olinto MTA, Paniz VMV. Conhecimento sobre a farmacoterapia por portadores de Hipertensão Arterial Sistêmica. Ciênc Saúde Coletiva. 2013;18(8):2263-74.

New York Heart Association. The Criteria Committee of the New York Heart Association. Nomenclature and criteria for diagnosis of diseases of the heart and great vessels. 9. ed. Boston: Little Brown & Co; 1994.

Menezes Júnior AS, Moreira HG, Daher MT. Análise da variabilidade da frequência cardíaca em pacientes hipertensos, antes e depois do tratamento com inibidores da enzima conversora da angiotensina II. Arq Bras Cardiol. 2004;83(2):165-8.

Tibana RA, Boullosa DA, Leicht AS, Prestes J. Women with metabolic syndrome present different autonomic modulation and blood pressure response to an acute resistance exercise session compared with women without metabolic syndrome. Clin Physiol Funct Imaging. 2013;33(5):364-72.

Meersman RE. Heart rate variability and aerobic fitness. Am Heart J. 1993;125:726-31.

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Published

2016-06-14

Issue

Vol. 14 No. 49 (2016): Revista de Atenção à Saúde

Section

ARTIGOS ORIGINAIS

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