Quality of life of elderly benzodiazepinic users
DOI:
https://doi.org/10.13037/ras.vol15n52.4558Keywords:
Benzodiazepines, Elderly, Life qualityAbstract
Introduction: The prevalence of benzodiazepine prescription for the elderly is high, but this class of drugs is potentially inappropriate due to possible adverse reactions. Changes due to aging may interfere with the pharmacokinetics and pharmacodynamics of medicinal products. Long-acting benzodiazepines like Diazepam are more likely to involve older people in serious accidents. Objective: The objective of this study was to evaluate the quality of life of the elderly who attended the SUS in the city of Alfenas, who use continuous benzodiazepine. Materials and methods: A cross-sectional study was carried out with 100 elderly patients using a generic instrument of quality of life evaluation, SF-36 (Item Short-Form Health Survey). Data collection was performed between June and September 2016, at the Medicinal Distribution Center (CDM) in the city of Alfenas, through interviews conducted at the time of the benzodiazepine dispensation. Results: The statistical analysis showed no significant correlation between the means, thus demonstrating that there was no change in the quality of life of Diazepam users when compared with other benzodiazepines. It was observed that 71 (71%) of the patients were female. The most commonly used benzodiazepine was Clonazepam (68%), followed by Diazepam (26%), Lorazepam (4%) and Bromazepam (2%), respectively. Regarding QOL, the most compromised SF-36 was the physical aspect (44.6). The best index was found in the social aspects dimension (63.9). Conclusions: The findings of this study show that there is a general compromise in the quality of life of elderly benzodiazepine users, living in the city of Alfenas, Minas Gerais.
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References
Mosegui GBG, Rozenfeld S, Veras RPV, Vianna CMM.
Avaliação da qualidade do uso de medicamentos em idosos.
Rev Saúde Públ. 1999;33(5):437-44.
Loyola Filho AI, Uchoa E, Firmo JOA, Lima-Costa MF.
Estudo de base populacional sobre o consumo de medicamentos
entre idosos: Projeto Bambuí. Cad. Saúde Pública.
;21(2):545-53.
Cruz AV, Fulone I, Alcalá M, Fernandes AA, Montebelo
MI, Lopes LC. Uso crônico de diazepam em idosos atendidos
na rede pública em Tatuí-SP. Rev Ciênc Farm Básica
Apl. 2006;27(3):259-67.
Rang HP, Dale MM, Ritter JM, Flower RJ, Henderson G.
Farmacologia. 7ª ed. Rio de Janeiro: Elsevier; 2012.
Baldoni AO, Chequer FMD, Ferraz ERA, Oliveira DP,
Pereira LRL, Dorta DJ. Eldery and drugs: risks and necessity
of rational use. Braz J Pharm Sci. 2010;46(4):617-32.
Griffin CE III, Kaye AM, Bueno FR, Kaye AD.
Benzodiazepinepharmacology and central nervous system-
-mediated effects. Ochsner J. 2013;13(2):214-23.
Fick DM, Cooper JW, Wade WE, Waller JL, Maclean
JR, Beers MH. Updating the Beers criteria for potentially
inappropriate medication use in older adults: results
of a US consensus panel of experts. Arch Intern Med.
;163(22):2716-24.
Brasil. Ministério da Saúde. Fundação Nacional de Saúde.
Resolução nº 466, de 12 de dezembro de 2012, sobre pesquisas
envolvendo seres humanos. Brasília, DF: Ministério
da Saúde; 2013.
Ciconelli RM. Tradução para o português e validação do
questionário genérico de avaliação de qualidade de vida medical
outcomes study 36 – item short –form health survey
(SF-36). São Paulo. Tese [Doutorado em Ciências da Saúde
Aplicadas à Reumatologia] – Escola Paulista de Medicina de
São Paulo da Universidade Federal de São Paulo; 1997.
Soares DA, Toledo JAS, Santos LF, Lima RMB, Galdeano
LE. Qualidade de vida de portadores de insuficiência cardíaca.
Acta Paul Enferm. 2008;21(2):243-48.
IBM Corp. Released 2013. IBM SPSS Statistics for
Windows, Version 22.0. Armonk, NY: IBM Corp; 2013.
Olfson M, Marcus SC, Druss B, Elinson L, Tanelian T,
Pincus HA. National trends in the outpatient treatment of
depression. JAMA. 2014;287(2):203-9.
Alvarenga JM, Giacomin KC, Loyola Filho AI, Uchôa E,
Firmo JOA. Uso crônico de benzodiazepínicos entre idosos.
Rev Saúde Pública. 2014;48(6):866-72.
Azevedo AJP, Araújo AA, Ferreira MAF. Consumo de ansiolíticos
benzodiazepínicos: uma correlação entre dados do
SNGPC e indicadores sociodemográficos nas capitais brasileiras.
Ciênc Saúde coletiva. 2016;21(1):83-90.
Alvarenga JM, Loyola Filho AI, Giacomin KC, Uchoa E,
Firmo AO. Uso de benzodiazepínicos entre idosos: o alívio
de “jogar água no fogo”, para não pensar e dormir. Rev Bras
Geriatr Gerontol. 2015;18(2):249-58.
Telles Filho PCP, Chagas AR, Pinheiro MLP, Lima AMJ,
Durão AMS. Utilização de benzodiazepínicos por idosos de
uma estratégia de saúde da família: implicações para a enfermagem.
Esc Anna Nery Rev Enferm. 2011;15(3):581-86.
Naloto DCC. Prescrição de benzodiazepínicos para adultos
e idosos de um ambulatório de saúde mental. Ciênc Saúde
Coletiva. 2016;21(4):1267-76.
McIntosh B, Clark M, Spry C. Benzodiazepines in older
adults: a review of clinical effectiveness, cost-effectiveness,
and guidelines. [Internet]. Ottawa (ON): Canadian Agency
for Drugs and Technologies in Health; 2011 jan. [acesso em
jun. 13]. Disponível em: https://goo.gl/RXS5ID.
Carvalho MV, Siqueira LB, Sousa ALL, Jardim PCBV.
The influence of hypertension on quality of life. Arq Bras
Cardiol. 2013;100(2):164-74.
Pimenta FAP, et al. Avaliação da qualidade de vida de aposentados
com a utilização do questionário SF-36. Rev Assoc
Med Bras. (1992). 2008;54(1):55-60.
Campolina AG, Dini PS, Ciconelli RM. Impacto da doença
crônica na qualidade de vida de idosos da comunidade
em São Paulo (SP, Brasil). Ciênc Saúde Coletiva.
;16(6):2919-25.
Coelho ESP, Pedroso MFBP. Avaliação da qualidade de
vida em idosos residentes no município de Santos/SP. Rev
Ceciliana. 2012;4(1):4-8.
Santos, PR. Relação do sexo e da idade com nível de qualidade
de vida em renais crônicos hemodialisados. Rev Assoc
Med Bras. (1992). 2006;52(5):356-59.
Nordon DG, Hübner CVK. Prescrição de benzodiazepínicos
por clínicos gerais. Diagn Tratamento. 2009;14(2):66-9.
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